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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
37.27
Human Site:
S442
Identified Species:
63.08
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
S442
S
T
F
L
A
F
P
S
P
E
K
L
L
R
L
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
S442
S
T
F
L
A
F
P
S
P
E
K
L
L
R
L
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
S496
S
T
F
L
A
F
P
S
P
E
K
L
L
R
L
Dog
Lupus familis
XP_538355
1323
142434
S442
S
T
F
L
A
F
P
S
P
E
K
L
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
S444
S
T
F
L
S
F
P
S
P
E
K
L
L
R
L
Rat
Rattus norvegicus
NP_001012199
431
46388
G291
I
A
D
A
V
R
G
G
L
P
K
L
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
S444
S
T
F
L
A
F
P
S
P
E
K
L
L
R
L
Chicken
Gallus gallus
NP_001006237
580
63057
S435
A
T
F
L
A
F
P
S
P
E
K
L
L
R
L
Frog
Xenopus laevis
O13066
580
62889
S435
S
T
F
L
S
F
P
S
P
E
K
L
V
R
M
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
S420
S
S
F
L
S
F
P
S
P
D
K
L
L
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
A445
A
S
E
T
F
A
V
A
N
K
T
I
S
Q
K
Honey Bee
Apis mellifera
XP_395378
580
63771
L419
N
G
E
N
L
L
L
L
Q
D
D
I
I
Q
D
Nematode Worm
Caenorhab. elegans
P34342
960
105635
A601
E
C
L
R
K
S
I
A
V
G
G
E
N
R
L
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
T247
N
L
N
D
N
T
F
T
A
R
G
A
K
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
100
100
100
N.A.
93.3
20
N.A.
100
93.3
80
80
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
100
100
100
N.A.
40
33.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
8
43
8
0
15
8
0
0
8
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
15
8
0
0
0
8
% D
% Glu:
8
0
15
0
0
0
0
0
0
58
0
8
0
8
0
% E
% Phe:
0
0
65
0
8
65
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
8
0
8
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
15
8
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
8
72
0
15
0
8
% K
% Leu:
0
8
8
65
8
8
8
8
8
0
0
72
58
0
72
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
15
0
8
8
8
0
0
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
65
0
65
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
15
0
% Q
% Arg:
0
0
0
8
0
8
0
0
0
8
0
0
0
72
0
% R
% Ser:
58
15
0
0
22
8
0
65
0
0
0
0
8
0
0
% S
% Thr:
0
58
0
8
0
8
0
8
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
8
0
8
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _